PDGF-BB Homodimer (Active) Protéine

N° du produit ABIN7520387

Cette protéine Recombinant est exprimée dans Yeast (Pichia pastoris).

Aperçu rapide pour PDGF-BB Homodimer (Active) Protéine (ABIN7520387)

Antigène: PDGF-BB Homodimer

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Yeast (Pichia pastoris)

Détail du produit

Fonction: Recombinant Human PDGF-BB Protein

Séquence: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT

Specificité: Ser82-Thr190

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1EU/μg

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized PDGF-BB at 2 μg/mL (100 μL/well) can bind Human PDGFRB with a linear range of 0.1-104.7 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.3 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc, pH 4.5.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: PDGF-BB Homodimer

Autre désignation: PDGF-BB

Sujet:

Description: Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.

Name: SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2,PDGF subunit B,PDGF-BB,PDGFB

ID gène: 5155

UniProt: P01127