Cofilin 2 Protein (CFL2) (His tag)

N° du produit ABIN7668552

Protéine Recombinant Cofilin 2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Cofilin 2 Protein (CFL2) (His tag) (ABIN7668552)

Antigène: Cofilin 2 (CFL2)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 98 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Cofilin 2 protéine est marqué à la His tag.

Fonction: Recombinant Human CFL2/cofilin 2/ADF Protein (His Tag)

Séquence: Ala 2-Leu 166

Purification: > 98 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Cofilin 2 (CFL2)

Autre désignation: CFL2

Sujet: NEM7,Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH -dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.

Poids moléculaire:

Calculated MW: 20.4 kDa

Observed MW: 21 kDa

ID gène: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis