Desmin Protein (DES) (AA 2-470) (His tag)
Aperçu rapide pour Desmin Protein (DES) (AA 2-470) (His tag) (ABIN7668649)
Antigène
Voir toutes Desmin (DES) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 2-470
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Purification/Conjugué
- Cette Desmin protéine est marqué à la His tag.
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Fonction
- Recombinant Human DES Protein (His Tag)
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Séquence
- Ser2-Leu470
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Purification
- > 95 % as determined by reducing SDS-PAGE.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 10 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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Buffer
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- Desmin (DES)
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Autre désignation
- DES
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Sujet
- DES,Desmin,desmin,Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
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Poids moléculaire
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Calculated MW: 51.5 kDa
Observed MW: 58 kDa
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ID gène
- 1674
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UniProt
- P17661
Antigène
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