Desmin Protein (DES) (AA 260-470) (His tag)

N° du produit ABIN1096527

Détail du produit

Antigène: Desmin (DES)

Type de proteíne: Recombinant

Attributs du protein: AA 260-470

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Desmin protéine est marqué à la His tag.

Fonction: Recombinant Human Desmin (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MVEMDMSKPD LTAALRDIRA QYETIAAKNI SEAEEWYKSK VSDLTQAANK NNDALRQAKQ EMMEYRHQIQ SYTCEIDALK GTNDSLMRQM RELEDRFASE ASGYQDNIAR LEEEIRHLKD EMARHLREYQ DLLNVKMALD VEIATYRKLL EGEESRINLP IQTYSALNFR ETSPEQRGSE VHTKKTVMIK TIETRDGEVV SEATQQQHEV L

Attributs du produit: Recombinant Human Desmin is produced by our E. coli expression system. The target protein is expressed with sequence (Val260-Leu470) of Human DES fused with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: Desmin (DES)

Autre désignation: Desmin (DES Produits)

Synonymes: DES Protein, des-b Protein, MGC80853 Protein, des Protein, csm1 Protein, csm2 Protein, desm Protein, cmd1i Protein, MGC75911 Protein, LOC100220724 Protein, desmin Protein, cb290 Protein, fb59a12 Protein, wu:fb59a12 Protein, zgc:109859 Protein, CSM1 Protein, CSM2 Protein, LGMD2R Protein, wu:fc11d08 Protein, zgc:154009 Protein, des-a Protein, MGC52614 Protein, desmin Protein, desmin, gene 1 L homeolog Protein, desmin, gene 1 Protein, desmin a Protein, desmin b Protein, desmin, gene 1 S homeolog Protein, desmin, gene 2 S homeolog Protein, DES Protein, des.1.L Protein, des.1 Protein, des Protein, desma Protein, Des Protein, desmb Protein, des.1.S Protein, des.2.S Protein

Sub Type: Fusionprotein

Sujet: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
Alternative Names: Desmin, DES

Poids moléculaire: 26.7 kDa

UniProt: P17661