Galectin 3 Protein (LGALS3) (His tag)

N° du produit ABIN7668810

Protéine Recombinant Galectin 3 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Galectin 3 Protein (LGALS3) (His tag) (ABIN7668810)

Antigène: Galectin 3 (LGALS3)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Immunogen (Imm)

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Galectin 3 protéine est marqué à la His tag.

Fonction: Recombinant Human Galectin-3 Protein(His Tag)

Séquence: 2Ala-250Iie

Purification: SDS-PAGE analysis of Human Galectin-3 proteins, 2μg/lane of Recombinant Human Galectin-3 proteins was resolved with SDS-PAGE under reducing conditions, showing bands at 32 KD

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 10 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Galectin 3 (LGALS3)

Autre désignation: Galectin-3

Sujet: MAC,Galactose-specific lectin,Galactoside-Binding Soluble,Galectin,Lectin L,GAL,CBP,LGALS3,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2,Galactoside-Binding Soluble 3,Lectin,Galectin-3,Gal-3,L-31,35 kDa lectin,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,galactose binding,galactoside binding soluble 3,Galactoside-binding protein,galectin 3,Galectin 3 internal gene,Galectin3,GBP,IgE binding protein,included,L 31,L 34,L-34 galactoside-binding lectin,Lectin,Galactoside-Binding Soluble 3,LEG3,MAC 2 antigen,Mac-2,Macrophage galactose-specific lectin,MGC105387,P35,soluble 3,Galectin-3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. Galectin-3 has an important role in tumor progression throμgh inhibition of apoptosis. Galectin-3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of Galectin-3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with Galectin-3 include Follicular Adenoma and Papillary Carcinoma.

Poids moléculaire:

Calculated MW: 27.4 kDa

Observed MW: 32 kDa

ID gène: 3958

UniProt: P17931

Pathways: Signalisation RTK