IGF2 Protéine
Aperçu rapide pour IGF2 Protéine (ABIN7849658)
Antigène
Voir toutes IGF2 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Fonction
- Recombinant Human Insulin-like growth factors-2,IGF2 Protein
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM PBS, pH 7.4±0.2 with 0.1 % SKL as the preservative.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
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- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
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Autre désignation
- IGF2
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Sujet
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Synonyms: Insulin-like growth factor II, IGF2, IGF-II, Somatomedin-A, T3M-11-derived growth factor, Insulin-like growth factor II Ala-25 Del, Preptin, PP1446, IGF-2.
Description: Recombinant human IGF2 protein.
Background: Insulin-like growth factor 2 (IGF-2), also called somatomedin A, is a member of the insulin family of polypeptide growth factors. It is also one of three protein hormones that share structural similarity to insulin. In humans, the IGF2 gene is located on chromosome 11p15.5, extends over 30 kb and contains 8 exons. Scott et al. (1985) found that expression of the IGF2 gene was markedly increased relative to adult tissues, but was comparable to the level of expression in several fetal tissues including kidney, liver, adrenal, and striated muscle. Its functions include mediation of growth hormone action, stimulation of growth of cultured cells, stimulation of the action of insulin, and involvement in development and growth.
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Pathways
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
Antigène
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