IL1A Protéine

N° du produit ABIN7849667

Cette protéine Recombinant IL1A est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL1A Protéine (ABIN7849667)

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), ELISA

Pureté: >90 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human Interleukin-1 alpha, IL1A Protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM Tris-HCl, pH 7.4±0.2.

Stock: 4 °C,-20 °C

Stockage commentaire: Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL1A

Sujet:

Synonyms: Interleukin-1 alpha, IL1A, IL-1 alpha, Hematopoietin-1, IL1F1, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha.

Description: Recombinant human IL-1 alpha protein.

Background: Interleukin-1 alpha (IL-1α) is a protein of the interleukin-1 family that in humans is encoded by the IL1A gene which spans 10.2 kb and has 7 exons. It is 1 of 2 structurally distinct forms of IL1, the other being IL1B, this two proteins are synthesized by a variety of cell types, including activated macrophages, keratinocytes, stimulated B lymphocytes, and fibroblasts, and are potent mediators of inflammation and immunity. IL1A may play a role in the genesis of inflammation by augmenting the transcription of proinflammatory genes, a mechanism not affected by extracellular inhibitors. IL1A has been administered to patients during receiving autologous bone marrow transplantation.

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints