Thyroperoxidase Protéine

N° du produit ABIN7849670

Cette protéine Recombinant Thyroperoxidase est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Thyroperoxidase Protéine (ABIN7849670)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), ELISA

Pureté: >90 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human Thyroid peroxidase, TPOProtein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris-HCl ( pH 8.0).

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: TPO

Sujet:

Synonyms: Thyroid peroxidase, TPO, thyroperoxidase, iodide peroxidase

Description: Recombinant human TPO protein.

Background: Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. In humans, thyroperoxidase is encoded by the TPO gene. Thyroid peroxidase (TPO) deficiency, caused by biallelic TPO mutations, is a well-established genetic form of congenital hypothyroidism (CH). TPO mutations with residual activity are associated with mild TPO deficiency, which is clinically characterized by marked goiter, mild TSH elevation, high serum T3to T4Molar ratio, and high serum thyroglobulin levels.

Pathways: Thyroid Hormone Synthesis