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IL1A Protéine

Protéine Recombinant IL1A exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7849710
506,00 €
Plus frais de livraison 40,00 € et TVA
10 μg
Destination: France
Envoi sous 9 à 11 jours ouvrables

Aperçu rapide pour IL1A Protéine (ABIN7849710)

Antigène

Voir toutes IL1A Protéines
IL1A (Interleukin 1 alpha (IL1A))

Type de proteíne

Recombinant

Origine

  • 23
  • 16
  • 10
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Souris

Source

  • 48
  • 13
  • 9
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Pureté

>95 % by SDS-PAGE
  • Fonction

    Recombinant Mouse IL-1a Protein

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    <1 EU/μg by LAL test
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  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 6 % Sucrose, 2 %Mannitol, 50 mM Arginine, 0.03 % Tween80, pH 8.0.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
  • Antigène

    IL1A (Interleukin 1 alpha (IL1A))

    Autre désignation

    IL-1a

    Sujet

    Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α

    Description: Recombinant mouse IL-1a is produced by the E.coli system, with the target gene encoding Ser115-Ser270 expressed.

    Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.

    UniProt

    P01583

    Pathways

    Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
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