IL1A Protéine
Aperçu rapide pour IL1A Protéine (ABIN7849710)
Antigène
Voir toutes IL1A ProtéinesType de proteíne
Origine
Source
Application
Pureté
-
-
Fonction
- Recombinant Mouse IL-1a Protein
-
Stérilité
- 0.2 μm filtered
-
niveau d'endotoxine
- <1 EU/μg by LAL test
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 6 % Sucrose, 2 %Mannitol, 50 mM Arginine, 0.03 % Tween80, pH 8.0.
-
Stock
- 4 °C,-20 °C,-80 °C
-
Stockage commentaire
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
Autre désignation
- IL-1a
-
Sujet
-
Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α
Description: Recombinant mouse IL-1a is produced by the E.coli system, with the target gene encoding Ser115-Ser270 expressed.
Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.
-
UniProt
- P01583
-
Pathways
- Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
Antigène
-