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CNTF Protéine

Cette protéine Recombinant CNTF est produite dans Escherichia coli (E. coli).
N° du produit ABIN7849711
462,00 €
Plus frais de livraison 40,00 € et TVA
10 μg
Destination: France
Envoi sous 9 à 11 jours ouvrables

Aperçu rapide pour CNTF Protéine (ABIN7849711)

Antigène

Voir toutes CNTF Protéines
CNTF (Ciliary Neurotrophic Factor (CNTF))

Type de proteíne

Recombinant

Origine

  • 21
  • 10
  • 5
  • 2
  • 2
  • 1
Humain

Source

  • 30
  • 3
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Pureté

>95 % by SDS-PAGE
  • Fonction

    Recombinant Human CNTF Protein

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    <1 EU/μg by LAL test
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  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 6 % Sucrose, 4 % Mannitol, 0.05 % Tween 80, pH 8.0.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
  • Antigène

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    Autre désignation

    CNTF

    Sujet

    Synonyms: CNTF, Hciliary neurotrophic factor

    Description: Recombinant human CNTF is produced by the E.coli system, with the target gene encoding Ala2-Met200 expressed.

    Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. It is a hypothalamic neuropeptide that is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also cotranscribed with the upstream ZFP91 gene.

    UniProt

    P26441

    Pathways

    Signalistation JAK/STAT
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