ACVA Protéine

N° du produit ABIN7849716

Protéine Recombinant ACVA exprimée dans Human Cells.

Aperçu rapide pour ACVA Protéine (ABIN7849716)

Antigène: ACVA (Activin A (ACVA))

Type de proteíne: Recombinant

Origine: Humain, Souris

Source: Human Cells

Application: SDS-PAGE (SDS)

Pureté: >95 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human / Mouse/ Rat Activin A Protein

Stérilité: 0.2 μm filtered

niveau d'endotoxine: <0.01EU/μg by LAL test

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 4 mM HCl,4 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: ACVA (Activin A (ACVA))

Autre désignation: Activin A

Sujet:

Synonyms: Activin beta A chain,EDF,FRP,INHBA,Inhibin Beta A,Inhibin beta A chain,Inhibin β-A,inhibin,beta A

Description: Recombinant human Activin A is produced by the mammalian system, with the target gene encoding Gly311-Ser426 expressed.

Background: Activin A is a homodimer of 14 kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism