Thrombopoietin Protein (THPO) (AA 22-326)

N° du produit ABIN7866069

Cette protéine Recombinant Thrombopoietin est produite dans CHO Cells.

Aperçu rapide pour Thrombopoietin Protein (THPO) (AA 22-326) (ABIN7866069)

Antigène: Thrombopoietin (THPO)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Rat

Source: CHO Cells

Pureté: >95 % , as determined by SDS-PAGE and HPLC

Détail du produit

Attributs du protein: AA 22-326

Fonction: Rat THPO Protein Recombinant

Séquence: SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF

Attributs du produit:

Protein Size: Recombinant THPO migrates as an approximately 19 kDa protein due to glycosylation under reducing conditions in SDS-PAGE.

Sequence Position: Optimized DNA sequence encoding Rat THPO mature chain was expressed in CHO. Recombinant Rat Thrombopoietin encodes amino acid residues 22-326.

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg(1EU/μg).

Biological Activity Comment: Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Buffer: THPO was Lyophilized from PBS, pH 7.2.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this product can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Date de péremption: 24 months

Détail du antigène

Antigène: Thrombopoietin (THPO)

Autre désignation: THPO

Poids moléculaire: 19 kDa

Pathways: Signalistation JAK/STAT, Hormone Activity