M-CSF/CSF1 Protéine

N° du produit ABIN7866449

Protéine Recombinant M-CSF/CSF1 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour M-CSF/CSF1 Protéine (ABIN7866449)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Escherichia coli (E. coli)

Pureté: > 98 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Mouse M-CSF Protein

Séquence: MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP

Specificité: Chromosomal location:3 F3, 3 51.0 cM

Attributs du produit: Length (aa):156

Information d'application

Indications d'application: The biological activity was determined by the induction of proliferation in the NFS 60 cell line.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: water,Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-0.5 mg/mL. Do not vortex. This solution can be stored at 2-8 °C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1 % BSA) and store in working aliquots at -20 °C to -80 °C.

Buffer: PBS

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 12 months at -20°C to -80°C.

Date de péremption: 12 months

Détail du antigène

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: M-CSF

Sujet:

Synonyms: Csf1, op, Csfm, MCSF, C87615

Description: M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant murine M-CSF is a 36.4 kDa homodimeric protein containing two 156 amino acid polypeptide subunits.

Poids moléculaire: 36.4 kDa

ID gène: 12977

NCBI Accession: NM_007778, NP_031804

UniProt: P07141

Pathways: Signalisation RTK