IL-6 Receptor Protein (AA 20-358, Subunit alpha)

N° du produit ABIN7955874

Cette protéine Recombinant IL-6 Receptor est exprimée dans Insect cells (Sf21).

Aperçu rapide pour IL-6 Receptor Protein (AA 20-358, Subunit alpha) (ABIN7955874)

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Insect cells (Sf21)

Pureté: > 97 % by SDS-PAGE analyses.

Détail du produit

Attributs du protein: AA 20-358, Subunit alpha

Fonction: Recombinant Human Interleukin-6 Receptor Subunit Alpha

Séquence: Leu20-Asp358,

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 1 EU/ug of rHuIL-6 Ralpha as determined by LAL method.

Biological Activity Comment: Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.

Information d'application

Commentaires:

Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from 0.2 um filtered concentrated solution in PBS.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.

Date de péremption: 12 months

Détail du antigène

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: Interleukin-6 Receptor

Poids moléculaire: 50 kDa

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints