YWHAE Protéine

N° du produit ABIN7938557

Cette protéine Recombinant YWHAE est produite dans Escherichia coli (E. coli).

Aperçu rapide pour YWHAE Protéine (ABIN7938557)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant YWHAE protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant YWHAE protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: YWHAE

Sujet:

Protein Background: YWHAE (14-3-3 protein epsilon) also known as tyrosine 3-mono-oxygenase/tryptophan 5-monooxygenase activation protein is a member of the 14-3-3 family. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm. Plays a positive role in the antiviral signaling pathway upstream of TBK1 via interaction with RIGI. Mechanistically, directs RIGI redistribution from the cytosol to mitochondrial associated membranes where it mediates MAVS-dependent innate immune signaling during viral infection.

Short Description: Recombinant YWHAE protein that includes full length of human YWHAE protein (accession number NP_006752.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 31.34 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

Aliases: 14-3-3 protein epsilon, tyrosine 3-mono-oxygenase/tryptophan 5-monooxygenase activation protein, FLJ45465, Epsilon polypeptide

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase