14-3-3 zeta Protein (YWHAZ)

N° du produit ABIN7938564

Cette protéine Recombinant 14-3-3 zeta est produite dans Escherichia coli (E. coli).

Aperçu rapide pour 14-3-3 zeta Protein (YWHAZ) (ABIN7938564)

Antigène: 14-3-3 zeta (YWHAZ)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant YWHAZ protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant YWHAZ protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: 14-3-3 zeta (YWHAZ)

Autre désignation: YWHAZ

Sujet:

Protein Background: YWHAZ (14-3-3 protein zeta/delta) is a adapter protein, Implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation.

Short Description: Recombinant YWHAZ protein that includes full length of human YWHAZ protein (accession number NP_001129171.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 29.91 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

Aliases: 14-3-3 Protein Zeta/Delta, KCIP, Activation Protein, Delta Polypeptide, YWHAD, HEL4, Protein Kinase C, Inhibitor Protein 1

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location