ALKBH1 Protéine
Aperçu rapide pour ALKBH1 Protéine (ABIN7938582)
Antigène
Voir toutes ALKBH1 ProtéinesType de proteíne
Origine
Source
Application
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Fonction
- Recombinant ALKBH1 protein
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Attributs du produit
- ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 11.737,02 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 15.754,29 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (His tag)
custom-made ALKBH1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (His tag)custom-made ALKBH1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) protein (GST tag)ALKBH1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
AlkB, Alkylation Repair Homolog 1 (ALKBH1) protein (Myc-DYKDDDDK Tag)ALKBH1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant ALKBH1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
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Autre désignation
- ALKBH1
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Sujet
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Protein Background: ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.
Short Description: Full length ALKBH1 protein (accession number NP_006011.2) was expressed in E.coli cells with an N-terminal 6xHis Tag. The molecular weight of ALKBH1 is 47.6 kDa.
Aliases: AlkB Homolog 1, Histone H2A Dioxygenase
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Pathways
- Réparation de l'ADN
Antigène
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