Calmodulin 1 Protein (CALM1)

N° du produit ABIN7938673

Protéine Recombinant Calmodulin 1 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Calmodulin 1 Protein (CALM1) (ABIN7938673)

Antigène: Calmodulin 1 (CALM1)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant Calmodulin-1 protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant Calmodulin-1 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: Calmodulin 1 (CALM1)

Autre désignation: Calmodulin-1

Sujet:

Protein Background: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

Short Description: Recombinant Calmodulin-1 protein that includes full length of human Calmodulin-1 protein (accession number NP_001316851.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 19 kDa. The purity of the protein is ≥ 85 % by SDS-PAGE.

Aliases: DD132, PHKD1, CAMI, PHKD, Phosphorylase Kinase Delta,CAMII, CPVT4, CAM, CALML2, LQT14

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling