Glucagon Protein (GCG) (His tag)

N° du produit ABIN7938858

Cette protéine Recombinant Glucagon est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Glucagon Protein (GCG) (His tag) (ABIN7938858)

Antigène: Glucagon (GCG)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Purification/Conjugué: Cette Glucagon protéine est marqué à la His tag.

Fonction: Recombinant GLU protein

Attributs du produit: GLU protein was expressed in E. coli (accession number NP_001028216.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 43.1 kDa.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant GLU protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: Glucagon (GCG)

Autre désignation: GLU

Sujet:

Protein Background: GLU (Glutamine synthetase), also called as GLU, is an enzymatic that catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Short Description: GLU protein was expressed in E. coli cells (accession number NP_001028216.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 43.1 kDa.

Aliases: Glutamine synthetase

Poids moléculaire: 43.1 kDa

NCBI Accession: NP_001028216

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling