N6AMT1 Protéine
Aperçu rapide pour N6AMT1 Protéine (ABIN7939360)
Antigène
Voir toutes N6AMT1 ProtéinesType de proteíne
Origine
Source
Application
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Fonction
- Recombinant N6AMT1 protein
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant N6AMT1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol and 0.5 mM TCEP.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Stock
- -80 °C
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Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))
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Autre désignation
- N6AMT1
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Sujet
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Protein Background: DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women are unclear.N6AMT1(N-6 adenine-specific DNA methyltransferase 1) encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants.
Short Description: Recombinant N6AMT1 protein that includes full length of human N6AMT1 protein (accession number NP_037372.4) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 49.79 kDa.
Aliases: DNA N6-methyladenosine, N-6-Adenine-Specific DNA Methyltransferase 1, PRED28, KMT9, N6AMT, HEMK2, MTQ2, PRMC
Antigène
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