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N6AMT1 Protéine

Protéine Recombinant N6AMT1 exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7939360
616,92 €
Frais d'envoi 40,00 €, glace carbonique 20,00 € et TVA exclus
50 μg
Destination: France
Envoi sous 2 à 4 jours ouvrables

Aperçu rapide pour N6AMT1 Protéine (ABIN7939360)

Antigène

Voir toutes N6AMT1 Protéines
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))

Type de proteíne

Recombinant

Origine

Humain

Source

  • 7
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • Fonction

    Recombinant N6AMT1 protein
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    Produit
    Système d'expression
    Conjugué
    Origin
    Prix à partir de
    Système d'expression HEK-293 Cells
    Conjugué His tag
    Origin Human
    Prix à partir de 11.737,02 €
    Système d'expression Cell-free protein synthesis (CFPS)
    Conjugué Strep Tag
    Origin Human
    Prix à partir de 15.754,29 €

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  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Recombinant N6AMT1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol and 0.5 mM TCEP.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    Stock

    -80 °C

    Stockage commentaire

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • Antigène

    N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))

    Autre désignation

    N6AMT1

    Sujet

    Protein Background: DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women are unclear.N6AMT1(N-6 adenine-specific DNA methyltransferase 1) encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants.

    Short Description: Recombinant N6AMT1 protein that includes full length of human N6AMT1 protein (accession number NP_037372.4) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 49.79 kDa.

    Aliases: DNA N6-methyladenosine, N-6-Adenine-Specific DNA Methyltransferase 1, PRED28, KMT9, N6AMT, HEMK2, MTQ2, PRMC

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