PDGFRB Protein (AA 557-1106)

N° du produit ABIN7939425

Cette protéine Recombinant PDGFRB est exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour PDGFRB Protein (AA 557-1106) (ABIN7939425)

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Détail du produit

Attributs du protein: AA 557-1106

Fonction: Recombinant PDGFRB (557-1106) protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant PDGFRB (557-1106) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: PDGFRB

Sujet:

Protein Background: PDGFRB (Platelet Derived Growth Factor Receptor Beta), a tyrosine-protein kinase that acts as cell surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, PDGFRB plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration and plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. PDGFRB plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.

Short Description: Recombinant PDGFRB (557-1106) protein that includes amino acids 557-1106 of human PDGFRB protein (accession number NP_002600.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 63 kDa.

Aliases: Platelet Derived Growth Factor Receptor Beta

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling