PRDM4 Protéine

N° du produit ABIN7939442

Cette protéine Recombinant PRDM4 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour PRDM4 Protéine (ABIN7939442)

Antigène: PRDM4 (PR Domain Containing 4 (PRDM4))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant PRDM4 protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant PRDM4 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: PRDM4 (PR Domain Containing 4 (PRDM4))

Autre désignation: PRDM4

Sujet:

Protein Background: PRDM4 (PR/SET Domain 4) is a transcription factor of the PR-domain protein family. It contains a PRdomain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. PRDM4 recruits the chromatin modifier PRMT5, an arginine methyltransferase that catalyzes symmetric dimethylation of histone H4 arginine 3 (H4R3me2s) to exerts histone methyltransferase activity. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). Diseases associated with PRDM4 include Pseudo-Von Willebrand Disease and Porokeratosis.

Short Description: Recombinant PRDM4 protein was expressed in baculovirus expression system as the full length protein (accession number NP_036538.3) with a N-terminal FLAG tag. The molecular weight of the protein is 89.2 kDa.

Aliases: PR/SET Domain 4

Pathways: Neurotrophin Signaling Pathway