RANBP2 Protein (AA 2553-2838)

N° du produit ABIN7939502

Protéine Recombinant RANBP2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour RANBP2 Protein (AA 2553-2838) (ABIN7939502)

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Attributs du protein: AA 2553-2838

Fonction: Recombinant RANBP2 (2553-2838) protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant RANBP2 (2553-2838) protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Autre désignation: RANBP2

Sujet:

Protein Background: RANBP2 (E3 SUMO-protein ligase RanBP2) is a E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1.

Short Description: Recombinant RANBP2 (2553-2838) protein that includes amino acids 2553-2838 of human RANBP2 protein (accession number NP_006258.3) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 34.05 kDa. The purity of the protein is ≥ 90 % by SDS-PAGE.

Aliases: E3 SUMO-protein ligase, RanBP2, NUP358, ADANE, ANE1, P270, TRP1

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus