RHEB Protéine

N° du produit ABIN7939504

Cette protéine Recombinant RHEB est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour RHEB Protéine (ABIN7939504)

Antigène: RHEB (Ras Homolog Enriched in Brain (RHEB))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Fonction: Recombinant RHEB protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant RHEB protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: RHEB (Ras Homolog Enriched in Brain (RHEB))

Autre désignation: RHEB

Sujet:

Protein Background: RHEB (GTP-binding protein Rheb) is a is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in the regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Short Description: Recombinant RHEB protein that includes full length of the human RHEB protein (accession number NP_005605.1) was expressed in E.coli cells with an C-terminal His tag, The molecular weight of the protein is 21.56 kDa.

Aliases: GTP-binding protein Rheb, RHEB2, Ras Homolog Enriched In Brain 2

Pathways: Signalisation RTK