STAT4 Protéine
Aperçu rapide pour STAT4 Protéine (ABIN7939572)
Antigène
Voir toutes STAT4 ProtéinesType de proteíne
Origine
Source
Application
-
-
Fonction
- Recombinant STAT4 protein
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 11.737,02 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 15.754,29 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Recombinant STAT4 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
Stock
- -80 °C
-
Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
-
Autre désignation
- STAT4
-
Sujet
-
Protein Background: STAT4 (Signal transducer and activator of transcription 4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane and then dimerized STAT4 translocates to the nucleus to regulate gene expression. STAT4 play an essential role in a wide variety of cells and the pathogenesis of diverse human diseases, especially many kinds of autoimmune and inflammatory diseases, via activation by different cytokines through the Janus kinase (JAK)-STAT signaling pathway.
Short Description: Recombinant STAT4 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003142.1) with an N-terminal FLAG tag. The molecular weight of the protein is 87.21 kDa.
Aliases: SLEB11, DPMC
-
Pathways
- Signalistation JAK/STAT
Antigène
-