TET1 Protein (AA 1634-1986, AA 2601-2708)

N° du produit ABIN7939796

Cette protéine Recombinant TET1 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour TET1 Protein (AA 1634-1986, AA 2601-2708) (ABIN7939796)

Antigène: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Type de proteíne: Recombinant

Origine: Drosophila melanogaster

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Détail du produit

Attributs du protein: AA 1634-1986, AA 2601-2708

Fonction: Recombinant DmTet (1634-1986, 2601-2708) protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant DmTet (1634-1986 and 2601-2708) protein is supplied in 25 mM Tris pH 7.4, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Autre désignation: DmTet

Sujet:

Protein Background: Ten Eleven Translocation (TET) family proteins are cytosine oxygenases that catalyze the conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). 5hmC can be further oxidized into 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by TET proteins. Methylation at the C5 position of cytosine is an epigenetic modification of the mammalian genome that plays an important role in transcriptional regulation. TET proteins are responsible for initiating the enzymatic deamination process leading to cytosine demethylation.

Short Description: Recombinant DmTet (1634-1986 and 2601-2708) protein was expressed in E. colicells as the Protein fragment (accession number NP_001246581.1) with an N-terminal 6xHis tag. The molecular weight of DmTet (1634-1986 and 2601-2708) is 53.68 kDa.

Aliases: Drosophila melanogaster Tet-like protein

Pathways: Stem Cell Maintenance, L'effet Warburg