Complement Factor B Protein (CFB)
Aperçu rapide pour Complement Factor B Protein (CFB) (ABIN934807)
Antigène
Voir toutes Complement Factor B (CFB) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du produit
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Purified native Human Complement Factor B
Bioactivity: 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis
Protein Source: Human serum/plasma
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.2, no preservatives added,
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Agent conservateur
- Without preservative
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Précaution d'utilisation
- Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -80 °C
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Stockage commentaire
- Aliquot and store at -70 °C or lower.
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- Complement Factor B (CFB)
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Autre désignation
- Complement Factor B
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Sujet
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Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.
Description: Human serum/plasma.
Alternative Names: Recombinant CFB -
Poids moléculaire
- 93 kDa
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Pathways
- Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process
Antigène
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