Complement Factor B Protein (CFB)

N° du produit ABIN934807

Détail du produit

Antigène: Complement Factor B (CFB)

Type de proteíne: Native

Activité biologique: Active

Origine: Humain

Source: Human

Attributs du produit: Purified native Human Complement Factor B
Bioactivity: 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis
Protein Source: Human serum/plasma

Pureté: > 98 % pure

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.2, no preservatives added,

Agent conservateur: Without preservative

Précaution d'utilisation: Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -80 °C

Stockage commentaire: Aliquot and store at -70 °C or lower.

Détail du antigène

Antigène: Complement Factor B (CFB)

Autre désignation: Complement Factor B (CFB Produits)

Synonymes: AHUS4 Protein, BF Protein, BFD Protein, CFAB Protein, FB Protein, FBI12 Protein, GBG Protein, H2-Bf Protein, PBF2 Protein, bf Protein, Bf-1 Protein, Brre-Bf Protein, zgc:114032 Protein, Bf Protein, Sp152 Protein, bfb-A Protein, Bf B Protein, LOC397725 Protein, bf/c2 Protein, CFB Protein, AI195813 Protein, AI255840 Protein, B Protein, C2 Protein, Fb Protein, Da1-24 Protein, complement factor B Protein, complement factor B S homeolog Protein, complement factor B L homeolog Protein, CFB Protein, cfb Protein, bf Protein, cfb.S Protein, cfb.L Protein, bf/c2 Protein, LOC100555981 Protein, Cfb Protein

Sujet: Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.
Description: Human serum/plasma.
Alternative Names: Recombinant CFB

Poids moléculaire: 93 kDa

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process