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PCNA Protein (AA 1-261)
PCNA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % pure
SDS
Détail du produit
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Antigène
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PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Type de proteíne
Recombinant
Attributs du protein
AA 1-261
Origine
Toutes les origines à travers PCNA Protéines
Humain
Source
Toutes les sources à travers PCNA Protéines
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
Séquence
MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S
Attributs du produit
Purified recombinant Human PCNA protein Expression System: E.coli Molecular weight on SDS-PAGE will appear higher.
Pureté
> 95 % pure
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Alternatives
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Information d'application
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Indications d'application
PCNA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Supplied as a liquid in 20 mM Tris, pH 7.5, containing 0 mM EDTA, and 20 % glycerol.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
RT/-20 °C
Stockage commentaire
Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
Détail du antigène
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Antigène
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Autre désignation
PCNA (PCNA Produits )
Synonymes
PCNAR Protein, Pcna/cyclin Protein, pcna Protein, AO090003000846 Protein, 53/13 Protein, CG9193 Protein, DmPCNA Protein, Dmel\\CG9193 Protein, MUS209 Protein, Mus209 Protein, PCNA Protein, PCNA/mus209 Protein, Pcna Protein, dPCNA Protein, l(2)02448 Protein, l(2)56F Protein, l(2)56Fa Protein, l(2)s1534 Protein, cb16 Protein, fb36g03 Protein, wu:fa28e03 Protein, wu:fb36g03 Protein, pcna-A Protein, proliferating cell nuclear antigen Protein, DNA polymerase III sliding clamp Protein, Proliferating cell nuclear antigen Protein, Proliferating cell nuclear antigen-like Protein, proliferating cell nuclear antigen L homeolog Protein, proliferating cell nuclear antigen 1 Protein, PCNA Protein, Pcna Protein, pcna Protein, MMP_RS08810 Protein, ANI_1_512014 Protein, AOR_1_1500154 Protein, MGC53867 Protein, pcna.L Protein, pcna1 Protein, LOC106420145 Protein, pcn1 Protein
Sujet
PCNA (Proliferating Cell Nuclear protein) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques. Alternative Names: PCNA protein, , Proliferating cell nuclear protein protein, MGC8367 protein, Proliferating cell nuclear protein protein
Poids moléculaire
28 kDa (261 AA)
Pathways
Telomere Maintenance , Réparation de l'ADN , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagy
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