CNTF Protein (AA 1-200)
Aperçu rapide pour CNTF Protein (AA 1-200) (ABIN935113)
Antigène
Voir toutes CNTF ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-200
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Séquence
- MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
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Attributs du produit
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Purified recombinant CNTF protein
Expression System: E.coli
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Procédure de l'essai
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CNTF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, with 0 mM DTT, and 10 % glycerol.
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Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C or -70 °C for long term storage.
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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Autre désignation
- CNTF
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Sujet
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CNTF (Ciliary neurotrophic factor) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. This protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF protein is structurally related to leukemia inhibitory factor (LIF), interleukin-6 (IL-6), interleukin-11 (IL-11) and oncostatin M (OSM). It is localized in the cell nucleus subsequent to receptor binding. Recombinant human CNTF protein was expressed in E.coli and purified by using conventional chromatography techniques.
Alternative Names: Ciliary neurotrophic factor protein -
Poids moléculaire
- 22.9 kDa
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Pathways
- Signalistation JAK/STAT
Antigène
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