Cytokeratin 18 Protéine
Aperçu rapide pour Cytokeratin 18 Protéine (ABIN935141)
Antigène
Voir toutes Cytokeratin 18 (KRT18) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du produit
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Purified native Bovine Keratin K18 Protein
Protein Source: Bovine liver
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Keratin 18 (KRT18) (AA 1-430) protein (His tag)
KRT18 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Keratin 18 (KRT18) (AA 1-430) protein (GST tag)KRT18 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- Supplied in lyophilized form with 30 mM Tris/HCI pH 8.0, 9 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride.
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Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Autre désignation
- Keratin K18
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Sujet
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Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Description: Bovine liver.
Alternative Names: Keratin K 18, Cytokeratin 18 protein, Keratin 18 protein, Keratin K-18, Keratin K18, Keratin K-18 protein, Keratin K 18 protein -
Poids moléculaire
- 45 kDa
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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