Cytokeratin 18 Protéine

N° du produit ABIN935173

Détail du produit

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Attributs du produit: Purified recombinant Human Cytokeratin 18 protein
Expression System: E.coli

Pureté: > 95 % pure

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: Supplied in lyophilized form with 30 mM Tris/HCI pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.

Détail du antigène

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Autre désignation: Keratin K18 (KRT18 Produits)

Synonymes: CK18 Protein, K18 Protein, Krt1-18 Protein, CYK18 Protein, DreK18 Protein, cb83 Protein, dapk1 Protein, sb:cb83 Protein, wu:fa13f02 Protein, wu:fb36b04 Protein, krt18 Protein, MGC64569 Protein, MGC75922 Protein, KRT18 Protein, CK-18-A Protein, K18-A Protein, NC-11 Protein, cyk18 Protein, k18 Protein, krt18-a Protein, krt18-b Protein, krt18a Protein, xkendob Protein, keratin 18 Protein, keratin 18, type I L homeolog Protein, keratin 18, type I Protein, keratin, type I cytoskeletal 18 Protein, K18, simple type I keratin Protein, Keratin, type I cytoskeletal 18 Protein, keratin 18, type I S homeolog Protein, Krt18 Protein, KRT18 Protein, krt18 Protein, krt18.L Protein, LOC700569 Protein, LOC100136778 Protein, k1c18 Protein, LOC100008885 Protein, krt18.S Protein

Sujet: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Alternative Names: Keratin K18, Keratin K-18, Cytokeratin 18 protein, Keratin K 18, Keratin K-18 protein, Keratin 18 protein, Keratin K 18 protein

Poids moléculaire: 45 kDa

Pathways: Apoptose, Caspase Cascade in Apoptosis