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IL-13 Protéine

IL13 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 98 % pure Active
N° du produit ABIN935476
  • Antigène Voir toutes IL-13 (IL13) Protéines
    IL-13 (IL13) (Interleukin 13 (IL13))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 26
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 29
    • 16
    • 8
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Séquence
    MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
    Attributs du produit
    Purified recombinant Mouse IL13 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was 2.5 x 10^5 units/mg.
    Pureté
    > 98 % pure
    niveau d'endotoxine
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL13 Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Note: Slow to disolve.
    Buffer
    Lyophilized from 10 mM sodium citrate, pH 4.0.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    RT/-20 °C
  • Antigène
    IL-13 (IL13) (Interleukin 13 (IL13))
    Autre désignation
    IL13 (IL13 Produits)
    Synonymes
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Sujet
    IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma.
    Alternative Names: Interleukin 13 protein, NC300 protein, IL-13 protein, IL 13 protein, IL-13, IL-13 protein, Human P600 protein, IL 13, IL13
    Poids moléculaire
    12.3 kDa
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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