IL16 Protéine
Aperçu rapide pour IL16 Protéine (ABIN935481)
Antigène
Voir toutes IL16 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
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Attributs du produit
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Purified recombinant Human IL16 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 5 mM Na3PO4, pH 7.6.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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: "IL-16 signaling specifically induces STAT6 activation through CD4." dans: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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: "IL-16 signaling specifically induces STAT6 activation through CD4." dans: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).
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- IL16 (Interleukin 16 (IL16))
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Autre désignation
- IL16
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Sujet
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IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
Alternative Names: Interleukin 16 protein, IL 16 protein, IL-16, IL16, LCF protein, IL-16 protein, IL-16 protein, Lymphocyte Chemoattractant Factor protein, IL 16 -
Poids moléculaire
- 13.5 kDa
Antigène
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