IL-10 Protéine
Aperçu rapide pour IL-10 Protéine (ABIN935529)
Antigène
Voir toutes IL-10 (IL10) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN
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Attributs du produit
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Purified recombinant Human IL10 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is less than 10ng/mL. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Lyophilized from 20 mM Na3PO4, pH 7.0.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- IL-10 (IL10) (Interleukin 10 (IL10))
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Autre désignation
- IL10
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Sujet
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IL10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL10 inhibits the expression of proinflammatory cytokines such as IL1 and TNFa. Like IL4, IL10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL10 active on Mouse cells, but Mouse IL10 is inactive on human cells.
Alternative Names: CSIF protein, B-TCGF protein, TGIF protein, IL 10 protein, Interleukin 10 protein, IL-10 protein, IL10, IL 10, IL-10 protein, IL-10 -
Poids moléculaire
- 18.7 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Antigène
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