M-CSF/CSF1 Protéine
Aperçu rapide pour M-CSF/CSF1 Protéine (ABIN935675)
Antigène
Voir toutes M-CSF/CSF1 (CSF1) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MEVSEHCSHM IGNGHLQILQ QLIDSQMETA CLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNE ACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP
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Attributs du produit
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Purified recombinant Human M-CSF protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse M-NFS-60 cells is 1 x 10^5 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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Autre désignation
- M-CSF
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Sujet
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M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation.
Alternative Names: CSF-1 protein, Macrophage Colony Stimulating Factor protein, MGI-IM protein -
Poids moléculaire
- 18.1 kDa
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Pathways
- Signalisation RTK
Antigène
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