Sonic Hedgehog Protein (SHH)
Aperçu rapide pour Sonic Hedgehog Protein (SHH) (ABIN935799)
Antigène
Voir toutes Sonic Hedgehog (SHH) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- IVIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRALDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
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Attributs du produit
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Purified recombinant Human Sonic Hedgehog protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce alkaline phosphatase production by C3H/10T1/2 (CCL-226) cells. The expected ED50 for this effect is 0.8-1.0 ?g/mL. -
Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Sonic Hedgehog (SHH) (AA 24-197), (Cys24IleIle-Mutant) (Active) protein
SHH Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Sonic Hedgehog (SHH) (AA 25-198), (Cys25IleIle-Mutant) (Active) proteinSHH Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Sonic Hedgehog (SHH) (AA 181-280) protein (GST tag)SHH Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Sonic Hedgehog (SHH) protein (His tag)SHH Origine: Souris Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Sonic Hedgehog (SHH) (Active) protein (His tag)SHH Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Sonic Hedgehog (SHH) protein (His tag)SHH Origine: Humain Hôte: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Sonic Hedgehog (SHH) (AA 25-198) protein (His tag)SHH Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS
Sonic Hedgehog (SHH) (Active) proteinSHH Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
Sonic Hedgehog (SHH) (AA 24-197) protein (His tag)SHH Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Sonic Hedgehog (SHH) proteinSHH Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Supplied as a lyophilized powder. Sterile filtered through a 0.2 micron filter. Lyophilized from 1x PBS.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C to -80 °C for long term storage.
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- Sonic Hedgehog (SHH)
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Autre désignation
- Sonic Hedgehog
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Sujet
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Sonic the hedgehog homolog is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog and Indian hedgehog. SHH is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain.
Alternative Names: SHH protein -
Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
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