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Thrombopoietin Protein (THPO)

Protéine Recombinant Thrombopoietin exprimée dans Escherichia coli (E. coli).
N° du produit ABIN935857

Aperçu rapide pour Thrombopoietin Protein (THPO) (ABIN935857)

Antigène

Voir toutes Thrombopoietin (THPO) Protéines
Thrombopoietin (THPO)

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 14
  • 14
  • 5
  • 3
  • 2
  • 2
  • 2
Humain

Source

  • 27
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Pureté

> 98 % pure
  • Séquence

    SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF

    Attributs du produit

    Purified recombinant Human Thrombopoietin protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be 1 x 10^6 units/mg.

    niveau d'endotoxine

    < 0.1 ng per µg (1 EU/µg).
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  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Restore in water to a concentration of 0.5 - 1.0 mg/mL.

    Buffer

    Lyophilized from 10 mM Tris, pH 8.0.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Antigène

    Thrombopoietin (THPO)

    Autre désignation

    Thrombopoietin

    Sujet

    TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity.
    Alternative Names: c-MPL Ligand protein, TPO protein, THPO protein, Megakaryocyte colony-stimulating factor protein, MGDF protein

    Poids moléculaire

    18.7 kDa

    Pathways

    Signalistation JAK/STAT, Hormone Activity
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