VEGFC Protéine
Aperçu rapide pour VEGFC Protéine (ABIN935903)
Antigène
Voir toutes VEGFC ProtéinesType de proteíne
Origine
Source
Pureté
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Séquence
- MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR
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Attributs du produit
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Purified recombinant Human VEGF C protein
Expression System: HEK cells -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) (Active) protein (His-Avi Tag)
VEGFC Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) (Active) protein (Biotin,His-Avi Tag)VEGFC Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Vascular Endothelial Growth Factor C (VEGFC) (AA 1-419) protein (GST tag)VEGFC Origine: Humain Hôte: Wheat germ Recombinant AP, AA, ELISA, WB
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (His tag)VEGFC Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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Autre désignation
- VEGF C
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Sujet
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VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis.
Alternative Names: VRP protein, flt4 ligand protein, Vascular Endothelial Growth Factor-C protein -
Pathways
- Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2
Antigène
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