WISP3 Protéine

N° du produit ABIN935912

Détail du produit

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRKE KRLCYIQPCD SNILKTIKIP KGKTCQPTFQ LSKAEKFVFS GCSSTQSYKP TFCGICLDKR CCIPNKSKMI TIQFDCPNEG SFKWKMLWIT SCVCQRNCRE PGDIFSELKI L

Attributs du produit: Purified recombinant Human WISP3 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 0.2-0.3 µg/mL.

Pureté: > 98 % pure

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 10 M Acetic Acid o a concentration of 0.1 - 1.0 mg/mL.

Buffer: Supplied lyophilized from 10 mM CH3COOH.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Détail du antigène

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Autre désignation: WISP3 (WISP3 Produits)

Synonymes: CCN6 Protein, LIBC Protein, PPAC Protein, PPD Protein, ENSMUSG00000062074 Protein, Gm735 Protein, WISP-3 Protein, RGD1564120 Protein, WISP3 Protein, si:dkey-119m7.6 Protein, WNT1 inducible signaling pathway protein 3 Protein, WISP3 Protein, Wisp3 Protein, wisp3 Protein

Sujet: WISP-3 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is predominantly expressed in the adult kidney, testis and fetal kidney and weaker expression in placenta, ovary, prostate, small intestine, and skeletally-derived cells. WISP-3 is required for normal postnatal skeletal growth and cartilage homeostasis. Human WISP-3 is a 36.8 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
Alternative Names: CCN6 protein, WISP 3 protein, WISP-3, WISP-3 protein, WNT-1 inducible signaling pathway protein-3 protein, WISP-3 protein, WISP 3, WISP3

Pathways: Signalisation WNT, Growth Factor Binding