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PSMC3 Produits

(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Catégories

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008].

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Catégories PSMC3 en vedette

PSMC3 Anticorps

High quality antibodies with extensive validation data.

PSMC3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PSMC3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (7)
N° du produit ABIN3022705
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Rat
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (9)
N° du produit ABIN5542634
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Rat
Application WB, IHC, IF, IHC (p)
Validations
  • (10)
N° du produit ABIN1501335
Quantité 100 μL
Fiche technique Fiche technique

PSMC3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316603
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316601
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3086525
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PSMC3

Marshall, Watson, Hallengren, Walters, Dobrunz, Francillon, Wilson, Phillips, Wilson: "Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14)." dans: PLoS ONE, Vol. 8, Issue 12, pp. e84042, (2013) (PubMed).

Thompson, Harris, Brody: "Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor." dans: International journal of cancer. Journal international du cancer, Vol. 111, Issue 3, pp. 338-47, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à PSMC3

proteasome 26S subunit, ATPase 3 (PSMC3), proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), proteasome 26S subunit, ATPase 3 (Psmc3), 26S protease regulatory subunit 6A (HCAG_00069), 26S protease regulatory subunit 6A (GL50803_4365), 26S protease regulatory subunit 6A (EDI_316920), 26S protease regulatory subunit 6a (CpipJ_CPIJ006888), 26S protease regulatory subunit 6a (CpipJ_CPIJ006889), 26S protease regulatory subunit 6a (CpipJ_CPIJ010864), 26S protease regulatory subunit 6A (prs6a), proteasome 26S subunit, ATPase 3 (psmc3), 26S protease regulatory subunit 6A-B (LOC100115023), 26S protease regulatory subunit 6A (BBOV_IV004580), 26S protease regulatory subunit 6A, putative (CGB_M2140W), 26S protease regulatory subunit 6A (psmC3), 26S protease regulatory subunit 6A-B (LOC100637883), proteasome 26S subunit, ATPase 3 S homeolog (psmc3.S), nth-like DNA glycosylase 1 S homeolog (nthl1.S), 23.m06430, DDBDRAFT_0186002, DDBDRAFT_0232967, DDB_0186002, DDB_0232967, MGC89608, NV15940, psmc3, PSMC3, psmc3-a, psmc3-b, TBP-1, TBP1, tbp10, wu:fb39a02, zgc:86713

Protein level used designations for PSMC3

  • 26S protease regulatory subunit 6A
  • 26S proteasome AAA-ATPase subunit RPT5
  • TBP-1
  • Tat-binding protein 1
  • human immunodeficiency virus tat transactivator binding protein-1
  • proteasome 26S subunit ATPase 3
  • proteasome subunit P50
  • TAT-binding protein 1
  • Tat binding protein 1
  • spermatogenic cell/sperm-associated TAT-binding protein homolog SATA
  • 26S protease regulatory subunit 6a
  • proteasome (prosome, macropain) 26S subunit, ATPase, 3
  • proteasome 26S ATPase subunit 3
  • 26S protease regulatory subunit 6A-like
  • 26S proteasome ATPase 3 subunit
  • 26S protease regulatory subunit 6A-B
  • 26S proteasome AAA-ATPase subunit RPT5-B
  • TAT-binding protein 10
  • TBP-10
  • proteasome 26S subunit ATPase 3-B
  • 26S protease regulatory subunit 6A-A
  • 26S proteasome AAA-ATPase subunit RPT5-A
  • TAT-binding protein 6
  • TBP-6
  • proteasome (prosome, macropain) 26S subunit, ATPase 3
  • proteasome 26S subunit ATPase 3-A
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