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PSMD11 Produits

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Catégories

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].

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Catégories PSMD11 en vedette

PSMD11 Anticorps

High quality antibodies with extensive validation data.

PSMD11 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PSMD11 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7142202
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN389306
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6257765
Quantité 100 μL
Fiche technique Fiche technique

PSMD11 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6210729
Quantité 96 tests
Fiche technique Fiche technique

PSMD11 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316623
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3086642
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3124624
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PSMD11

Nath, Yu, Gipson, Marsh, Yoshidome, Robins, Todi, Housman, Lieberman: "Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction." dans: The Journal of clinical investigation, Vol. 128, Issue 8, pp. 3630-3641, (2018) (PubMed).

Tsakiri, Gaboriaud-Kolar, Iliaki, Tchoumtchoua, Papanagnou, Chatzigeorgiou, Tallas, Mikros, Halabalaki, Skaltsounis, Trougakos: "The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects." dans: Antioxidants & redox signaling, (2017) (PubMed).

Welk, Coux, Kleene, Abeza, Trümbach, Eickelberg, Meiners: "Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes." dans: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 13147-59, (2016) (PubMed).

Vilchez, Morantte, Liu, Douglas, Merkwirth, Rodrigues, Manning, Dillin: "RPN-6 determines C. elegans longevity under proteotoxic stress conditions." dans: Nature, Vol. 489, Issue 7415, pp. 263-8, (2012) (PubMed).

Vilchez, Boyer, Morantte, Lutz, Merkwirth, Joyce, Spencer, Page, Masliah, Berggren, Gage, Dillin: "Increased proteasome activity in human embryonic stem cells is regulated by PSMD11." dans: Nature, Vol. 489, Issue 7415, pp. 304-8, (2012) (PubMed).

Liu, Lee, Krummey, Lu, Cai, Lenardo: "The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease." dans: Nature immunology, Vol. 12, Issue 11, pp. 1063-70, (2011) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Sklirou, Gaboriaud-Kolar, Papassideri, Skaltsounis, Trougakos et al.: "6-bromo-indirubin-3'-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human ..." dans: Scientific reports, Vol. 7, Issue 1, pp. 11713 (PubMed).

Synonymes et noms alternatifs relatifs à PSMD11

proteasome 26S subunit, non-ATPase 11 (PSMD11), proteasome 26S subunit, non-ATPase 11b (psmd11b), proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (Psmd11), proteasome 26S subunit, non-ATPase 11 (Psmd11), 1700089D09Rik, 1810019E17Rik, 2610024G20Rik, 2810055C24Rik, C78232, p44.5, P44.5, psmd11, Rpn6, S9, wu:fb55b06, zgc:56580, zgc:77763

Protein level used designations for PSMD11

  • proteasome 26S non-ATPase subunit 11
  • 26S proteasome non-ATPase regulatory subunit 11B
  • 26S proteasome regulatory subunit RPN6-B
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
  • 26S proteasome non-ATPase regulatory subunit 11
  • 26S proteasome regulatory subunit 9
  • 26S proteasome regulatory subunit RPN6
  • 26S proteasome regulatory subunit S9
  • 26S proteasome regulatory subunit p44.5
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