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PTPN12 Protéines

(Protein Tyrosine Phosphatase G1 (PTPN12))

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

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PTPN12 Protein (AA 1-775) (His tag)

custom-made PTPN12 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ptpn12 Protein, UniprotID P35831

3 images

N° du produit ABIN7563191

Détails

PTPN12 Protein (AA 1-780) (His tag)

custom-made PTPN12 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PTPN12 Protein, UniprotID Q05209

3 images

N° du produit ABIN7551083

Détails

PTPN12 Protein (AA 2-300) (His-IF2DI Tag)

PTPN12 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Western Blotting (WB) image for Protein Tyrosine Phosphatase G1 (PTPN12) (AA 2-300) protein (His-IF2DI Tag) (ABIN7124676)

1 image

N° du produit ABIN7124676

Détails

PTPN12 Protein (AA 1-780) (GST tag)

PTPN12 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for Protein Tyrosine Phosphatase G1 (PTPN12) (AA 1-780) protein (GST tag) (ABIN1316826)

1 image

N° du produit ABIN1316826

Détails

PTPN12 Protein (AA 1-293) (His tag,GST tag)

PTPN12 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

N° du produit ABIN7421722

Détails

PTPN12 Protein (AA 1-293) (His tag)

PTPN12 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

N° du produit ABIN7419418

Détails

PTPN12 Protein (GST tag,His tag)

PTPN12 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active

N° du produit ABIN7317538

Détails

PTPN12 Protéine

PTPN12 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active

N° du produit ABIN7317537

Détails

PTPN12 Protein (AA 1-775) (Strep Tag)

custom-made PTPN12 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3133892

Détails

PTPN12 Protein (AA 1-780) (Strep Tag)

custom-made PTPN12 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3086687