PTPN12 Protéines
(Protein Tyrosine Phosphatase G1 (PTPN12))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
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12 Résultats
custom-made
PTPN12
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
PTPN12
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PTPN12
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
PTPN12
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
PTPN12
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
PTPN12
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
PTPN12
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
PTPN12
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 85 % as determined by reducing SDS-PAGE.
Active
custom-made
PTPN12
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
PTPN12
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
PTPN12
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Pseudonymes pour PTPN12 Protéines
protein tyrosine phosphatase, non-receptor type 12 (PTPN12) Protéinesprotein tyrosine phosphatase, non-receptor type 12 (Ptpn12) Protéines
P19-PTP Protéines
PTP-P19 Protéines
PTP-PEST Protéines
PTPG1 Protéines
Ptpg1 Protéines
RKPTP Protéines
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