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PTPRB Produits

(Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].

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Catégories PTPRB en vedette

PTPRB Anticorps

High quality antibodies with extensive validation data.

PTPRB Kits ELISA

Reliable ELISA kits for a wide range of species.

PTPRB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PTPRB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7443743
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7439990
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7444100
Quantité 100 μL
Fiche technique Fiche technique

PTPRB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962129
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511536
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method Quantitative
Validations
N° du produit ABIN1057846
Quantité 96 tests
Fiche technique Fiche technique

PTPRB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094830
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3131019
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094829
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PTPRB

Kim, Park, Kim, Noh, Park, Lie, Kim, Kim, Kwon: "SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 9, pp. 9842-9857, (2020) (PubMed).

Winderlich, Keller, Cagna, Broermann, Kamenyeva, Kiefer, Deutsch, Nottebaum, Vestweber: "VE-PTP controls blood vessel development by balancing Tie-2 activity." dans: The Journal of cell biology, Vol. 185, Issue 4, pp. 657-71, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à PTPRB

protein tyrosine phosphatase, receptor type B (PTPRB), receptor-type tyrosine-protein phosphatase beta (LOC100380677), protein tyrosine phosphatase, receptor type, B (Ptprb), protein tyrosine phosphatase, receptor type B (Ptprb), 3230402H02Rik, C130094E24, HPTP-BETA, HPTPB, PTPB, PTPRB, Ptpz, R-PTP-BETA, Rptpb, VE-PTP, VEPTP, Veptp

Protein level used designations for PTPRB

  • protein tyrosine phosphatase, receptor type, B
  • Receptor-type tyrosine-protein phosphatase beta
  • receptor-type tyrosine-protein phosphatase beta-like
  • receptor-type tyrosine-protein phosphatase beta
  • VE-PTP
  • protein tyrosine phosphatase, receptor type, beta polypeptide
  • vascular endothelial protein tyrosine phosphatase
  • R-PTP-beta
  • protein-tyrosine phosphatase beta
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