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PTPRA Produits

(Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

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Catégories PTPRA en vedette

PTPRA Anticorps

High quality antibodies with extensive validation data.

PTPRA Kits ELISA

Reliable ELISA kits for a wide range of species.

PTPRA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PTPRA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN1682399
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application IHC
Validations
  • (3)
N° du produit ABIN7260017
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN1049270
Quantité 50 μg
Fiche technique Fiche technique

PTPRA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951512
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1154921
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1154922
Quantité 96 tests
Fiche technique Fiche technique

PTPRA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN3086768
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN3133173
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN3113044
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PTPRA

Wu, Kao, Li, Chi, Lin: "Protein tyrosine-phosphatase expression profiling in gastric cancer tissues." dans: Cancer letters, Vol. 242, Issue 1, pp. 95-103, (2006) (PubMed).

Yahiro, Wada, Nakayama, Kimura, Ogushi, Niidome, Aoyagi, Yoshino, Yonezawa, Moss, Hirayama: "Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor." dans: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19183-9, (2003) (PubMed).

Zhang, Kondrikov, Yuan, Lin, Hansen, Lin: "Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells." dans: Oncogene, Vol. 22, Issue 43, pp. 6704-16, (2003) (PubMed).

Kapp, Metzinger, Kellerer, Häring, Lammers: "The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells." dans: Biochemical and biophysical research communications, Vol. 311, Issue 2, pp. 361-4, (2003) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." dans: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Zheng, Pallen: "Expression of receptor-like protein tyrosine phosphatase alpha in rat embryo fibroblasts activates mitogen-activated protein kinase and c-Jun." dans: The Journal of biological chemistry, Vol. 269, Issue 37, pp. 23302-9, (1994) (PubMed).

Zheng, Wang, Pallen: "Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase." dans: Nature, Vol. 359, Issue 6393, pp. 336-9, (1992) (PubMed).

Sap, DEustachio, Givol, Schlessinger: "Cloning and expression of a widely expressed receptor tyrosine phosphatase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 16, pp. 6112-6, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à PTPRA

protein tyrosine phosphatase, receptor type A (PTPRA), protein tyrosine phosphatase, receptor type A (ptpra), protein tyrosine phosphatase, receptor type, A (PTPRA), protein tyrosine phosphatase, receptor type, A (Ptpra), protein tyrosine phosphatase, receptor type, A (ptpra), protein tyrosine phosphatase, receptor type A S homeolog (ptpra.S), heptp, HEPTP, hlpr, HLPR, hptpa, HPTPA, hptpalpha, HPTPalpha, lrp, LRP, ptpa, PTPA, Ptpa, ptpa-a, Ptpalpha, PTPRA, ptprl2, PTPRL2, r-ptp-alpha, R-PTP-alpha, rptpa, RPTPA, Rptpalpha, RPTP[a], Rptra, Rptralpha, zf-RPTP[a]

Protein level used designations for PTPRA

  • protein tyrosine phosphatase, receptor type, A
  • receptor-type tyrosine-protein phosphatase alpha-like
  • Leukocyte common antigen-related peptide (protein tyrosine phosphate)
  • PTPLCA-related phosphatase
  • PTPase-alpha
  • protein tyrosine phosphatase, receptor type, alpha polypeptide
  • protein-tyrosine phosphatase alpha
  • receptor-type tyrosine-protein phosphatase alpha
  • tyrosine phosphatase alpha
  • LCA-related phosphatase
  • PTPTY-28
  • R-PTP-alpha
  • protein tyrosine phosphatase alpha
  • protein tyrosine phosphatase receptor type alpha
  • protein-tyrosine-phosphatase alpha
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