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PVRL1 Produits

(Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Catégories

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009].

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Catégories PVRL1 en vedette

PVRL1 Anticorps

High quality antibodies with extensive validation data.

PVRL1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PVRL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PVRL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, FACS, IHC, IF, LCI, ICC
Validations
  • (5)
N° du produit ABIN7043440
Quantité 25 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (2)
N° du produit ABIN519549
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (2)
N° du produit ABIN519548
Quantité 50 μg
Fiche technique Fiche technique

PVRL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969437
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969438
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958675
Quantité 96 tests
Fiche technique Fiche technique

PVRL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275307
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275308
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN6952290
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PVRL1

Bender, Whitbeck, Ponce de Leon, Lou, Eisenberg, Cohen: "Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry." dans: Journal of virology, Vol. 77, Issue 17, pp. 9542-52, (2003) (PubMed).

Yoon, Spear: "Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry." dans: Journal of virology, Vol. 76, Issue 14, pp. 7203-8, (2002) (PubMed).

Lopez, Cocchi, Avitabile, Leclerc, Adelaide, Campadelli-Fiume, Dubreuil: "Novel, soluble isoform of the herpes simplex virus (HSV) receptor nectin1 (or PRR1-HIgR-HveC) modulates positively and negatively susceptibility to HSV infection." dans: Journal of virology, Vol. 75, Issue 12, pp. 5684-91, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à PVRL1

nectin cell adhesion molecule 1 (NECTIN1), nectin-1 (LOC100145553), Poliovirus receptor-related protein 1 (pvrl1), nectin cell adhesion molecule 1 (nectin1), nectin cell adhesion molecule 1 (Nectin1), poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), nectin cell adhesion molecule 2 L homeolog (nectin2.L), AI835281, AW549174, CD111, Cd111, cd111, cd112, CLPED1, clped1, ED4, ed4, HIgR, higr, hveb, HVEC, HveC, hvec, nectin-1, nectin-2, OFC7, ofc7, PRR, prr, PRR1, prr1, prr2, PVRL1, pvrl1, pvrl2, pvrl2.L, PVRR, pvrr, PVRR1, pvrr1, pvrr2, SK-12, sk-12

Protein level used designations for PVRL1

  • ectodermal dysplasia 4 (Margarita Island type)
  • herpes virus entry mediator C
  • herpesvirus Ig-like receptor
  • nectin 1
  • poliovirus receptor-like 1
  • poliovirus receptor-related protein 1
  • poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin)
  • poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • Poliovirus receptor-related protein 1
  • herpesvirus entry mediator C
  • nectin-1 alpha
  • nectin-1 delta
  • nectin)
  • poliovirus receptor-related 1 (herpesvirus entry mediator C
  • nectin-1
  • poliovirus receptor-related 1
  • nectin
  • poliovirus receptor related protein
  • nectin 2
  • nectin cell adhesion molecule 2 L homeolog
  • nectin-2alpha
  • poliovirus receptor-related 2 (herpesvirus entry mediator B) L homeolog
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