PVRL4 Produits
(Poliovirus Receptor-Related 4 (PVRL4))
Catégories
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011].
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Catégories PVRL4 en vedette
PVRL4 Anticorps
High quality antibodies with extensive validation data.
PVRL4 Kits ELISA
Reliable ELISA kits for a wide range of species.
PVRL4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PVRL4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (5)
N° du produit
ABIN7237516
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7161114
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN1387848
Quantité
100 μL
Fiche technique
Fiche technique
PVRL4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958676
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510701
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730769
Quantité
96 tests
Fiche technique
Fiche technique
PVRL4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7275314
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275306
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275313
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PVRL4
: "Over-expression of Nectin-4 promotes progression of esophageal cancer and correlates with poor prognosis of the patients." dans: Cancer cell international, Vol. 19, pp. 106, (2019) (PubMed).: "Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins." dans: Viruses, Vol. 11, Issue 8, (2019) (PubMed).
: "Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17." dans: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6339-6351, (2017) (PubMed).
: "Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs." dans: Scientific reports, Vol. 7, Issue 1, pp. 349, (2017) (PubMed).
: "Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis." dans: Journal of dermatological science, Vol. 86, Issue 2, pp. 97-105, (2017) (PubMed).
: "A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development." dans: The Journal of biological chemistry, Vol. 291, Issue 11, pp. 5817-31, (2016) (PubMed).
: "Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer." dans: Cancer research, Vol. 75, Issue 1, pp. 22-30, (2015) (PubMed).
: "Nectin-4 expression contributes to tumor proliferation, angiogenesis and patient prognosis in human pancreatic cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 30, (2015) (PubMed).
: "SLAM- and nectin-4-independent noncytolytic spread of canine distemper virus in astrocytes." dans: Journal of virology, Vol. 89, Issue 10, pp. 5724-33, (2015) (PubMed).
: "Nectin-4 mutations causing ectodermal dysplasia with syndactyly perturb the rac1 pathway and the kinetics of adherens junction formation." dans: The Journal of investigative dermatology, Vol. 134, Issue 8, pp. 2146-2153, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à PVRL4
nectin cell adhesion molecule 4 (NECTIN4), nectin cell adhesion molecule 4 (nectin4), nectin cell adhesion molecule 4 (Nectin4), 1200017F15Rik, EDSS1, LNIR, nectin-4, Prr4, PRR4, PVRL4, RGD1559826, si:ch211-155e24.1Protein level used designations for PVRL4
- poliovirus receptor-related 4
- poliovirus receptor-related protein 4-like
- ig superfamily receptor LNIR
- nectin 4
- nectin-4
- poliovirus receptor-related protein 4
- Ig superfamily receptor LNIR
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