RAF1 Produits
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
Catégories
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
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Catégories RAF1 en vedette
RAF1 Anticorps
High quality antibodies with extensive validation data.
RAF1 Kits ELISA
Reliable ELISA kits for a wide range of species.
RAF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RAF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
- (1)
N° du produit
ABIN733208
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (1)
- (7)
N° du produit
ABIN3020713
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (5)
N° du produit
ABIN969560
Quantité
0.1 mg
Fiche technique
Fiche technique
RAF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960422
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380689
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380400
Quantité
2 x 96 tests
Fiche technique
Fiche technique
RAF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1317314
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5569962
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317315
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RAF1
: "Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer." dans: Cancer medicine, Vol. 7, Issue 4, pp. 1546-1559, (2018) (PubMed).: "EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer." dans: Molecular medicine reports, Vol. 17, Issue 6, pp. 7875-7885, (2018) (PubMed).
: "Wogonoside induces depalmitoylation and translocation of PLSCR1 and N-RAS in primary acute myeloid leukaemia cells." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 4, pp. 2117-2130, (2018) (PubMed).
: "Hypoxic postconditioning attenuates apoptosis via inactivation of adenosine A2a receptor through NDRG3-Raf-ERK pathway." dans: Biochemical and biophysical research communications, Vol. 491, Issue 2, pp. 277-284, (2017) (PubMed).
: "Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells." dans: Biochemical and biophysical research communications, Vol. 483, Issue 1, pp. 82-87, (2017) (PubMed).
: "Zika virus cell tropism in the developing human brain and inhibition by azithromycin." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 50, pp. 14408-14413, (2016) (PubMed).
: "The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection." dans: International journal of ophthalmology, Vol. 9, Issue 10, pp. 1371-1375, (2016) (PubMed).
: "Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling." dans: eLife, Vol. 5, (2016) (PubMed).
: "The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux." dans: Autophagy, Vol. 11, Issue 8, pp. 1373-88, (2015) (PubMed).
: "Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementia." dans: Behavioural brain research, Vol. 265, pp. 171-80, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à RAF1
Raf-1 proto-oncogene, serine/threonine kinase (RAF1), Raf-1 proto-oncogene, serine/threonine kinase (Raf1), Raf-1 proto-oncogene, serine/threonine kinase a (raf1a), Raf-1 proto-oncogene, serine/threonine kinase (raf1), v-raf-leukemia viral oncogene 1 (Raf1), Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S), 6430402F14Rik, AA990557, BB129353, c-Raf, c-raf, CRAF, craf, cRaf, Craf1, D830050J10Rik, NS5, raf, Raf-1, raf1, RAF1, v-RafProtein level used designations for RAF1
- Oncogene RAF1
- RAF proto-oncogene serine/threonine-protein kinase
- proto-oncogene c-RAF
- raf proto-oncogene serine/threonine protein kinase
- C-RAF
- cRaf
- murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV)
- raf-1
- v-raf-1 murine leukemia viral oncogene homolog 1
- murine leukemia viral oncogene homolog
- serine/threonine protein kinase RAF1
- MIL proto-oncogene serine/threonine-protein kinase
- RAF-1
- c-mil protein
- murine leukemia viral (v-raf-1) oncogene homolog 1
- RAF proto-oncogene serine/threonine-protein kinase-like
- Craf1 transforming
- murine sarcoma 3611 oncogene 1
- sarcoma 3611 oncogene
- v-raf-1 leukemia viral oncogene 1
- Proto-oncogene c-RAF
- Raf-1
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