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RAD9A Produits

(RAD9 Homolog A (S. Pombe) (RAD9A))

Catégories

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Catégories RAD9A en vedette

RAD9A Anticorps

High quality antibodies with extensive validation data.

RAD9A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RAD9A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (6)
N° du produit ABIN3022652
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF, ICC
Validations
  • (5)
N° du produit ABIN2857053
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), DB
Validations
  • (2)
  • (3)
N° du produit ABIN389633
Quantité 400 μL
Fiche technique Fiche technique

RAD9A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6206964
Quantité 96 tests
Fiche technique Fiche technique

RAD9A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317298
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3094931
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3137560
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RAD9A

Awate, De Benedetti: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." dans: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).

Yun, Shi, Yang, Zhang, Wang, Zhou, Mu: "Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy." dans: Scientific reports, Vol. 4, pp. 7548, (2015) (PubMed).

Kelly, Davey: "Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit." dans: PLoS ONE, Vol. 8, Issue 12, pp. e85859, (2013) (PubMed).

Ronald, Awate, Rath, Carroll, Galiano, Dwyer, Kleiner-Hancock, Mathis, Vigod, De Benedetti: "Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy." dans: Genes & cancer, Vol. 4, Issue 1-2, pp. 39-53, (2013) (PubMed).

Warmerdam, Brinkman, Marteijn, Medema, Kanaar, Smits: "UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway." dans: Journal of cell science, Vol. 126, Issue Pt 9, pp. 1923-30, (2013) (PubMed).

Mohni, Dee, Smith, Schumacher, Weller: "Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins." dans: Journal of virology, Vol. 87, Issue 1, pp. 531-42, (2012) (PubMed).

Bai, Madabushi, Guan, Lu: "Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1." dans: DNA repair, Vol. 9, Issue 5, pp. 478-87, (2010) (PubMed).

De Haro, Wray, Williamson, Durant, Corwin, Gentry, Osheroff, Lee, Hromas, Nickoloff: "Metnase promotes restart and repair of stalled and collapsed replication forks." dans: Nucleic acids research, Vol. 38, Issue 17, pp. 5681-91, (2010) (PubMed).

Ha, Lee, Palii, Brown, Takeda, Liu, Bhalla, Robertson: "Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery." dans: Human molecular genetics, Vol. 20, Issue 1, pp. 126-40, (2010) (PubMed).

Medhurst, Warmerdam, Akerman, Verwayen, Kanaar, Smits, Lakin: "ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage." dans: Journal of cell science, Vol. 121, Issue Pt 23, pp. 3933-40, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à RAD9A

RAD9 checkpoint clamp component A (RAD9A), RAD9 checkpoint clamp component A (Rad9a), RAD9 checkpoint clamp component A (rad9a), RAD9 checkpoint clamp component B (rad9b), RAD9 checkpoint clamp component A L homeolog (rad9a.L), MGC89062, RAD9, Rad9, rad9, rad9a, XRad9

Protein level used designations for RAD9A

  • DNA repair exonuclease rad9 homolog A
  • cell cycle checkpoint control protein RAD9A
  • hRAD9
  • RAD9 homolog A (S. pombe)
  • cell cycle checkpoint control protein RAD9A-like
  • Rad9-like protein
  • mRAD9
  • RAD9 homolog A
  • rCG47324-like
  • PCNA-like DNA checkpoint protein Rad9
  • RAD9 checkpoint clamp component A L homeolog
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