This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011].
Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: "Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3373-83, (2008) (PubMed).
Pseudonymes pour RAP1B Protéines
RAP1B, member of RAS oncogene family (RAP1B) Protéines RAP1B, member of RAS oncogene family (Rap1b) Protéines RAP1B, member of RAS oncogene family L homeolog (rap1b.L) Protéines RAP1B, member of RAS oncogene family (Bm1_39445) Protéines RAS related protein 1b (Rap1b) Protéines ras-related protein Rap-1b-like (LOC109067672) Protéines RAP1B, member of RAS oncogene family (rap1b) Protéines 2810443E11Rik Protéines cb119 Protéines cb1026 Protéines K-REV Protéines k-rev Protéines RAL1B Protéines ral1b Protéines Rap1b Protéines sb:cb119 Protéines wu:fb11c04 Protéines wu:fb74e09 Protéines wu:fk70e05 Protéines